1903
- Indiana University School of Medicine is founded
1921
- The Riley Memorial Association, now the Riley Children's Foundations, is founded with the goal of building a children's hospital in memory of Hoosier Poet James Whitcomb Riley
1924
- Riley Hospital for Children opens
1935
- President Franklin Delano Roosevelt attends the dedication of the hydrotheraputic pool for children with polio
1950
- The Riley Research Building opens as an addition to the Riley Hospital for Children campus
1951
- Indiana's first pediatric cardiac catheterization laboratory opens at Riley
1956
- Indiana's first pediatric open heart procedure is performed at Riley
1962
- Riley becomes the first hospital in the nation to perform percutaneous cardiac catheterization (a minimally invasive diagnostic and treatment procedure) in children
1966
- Riley Hospital for Children becomes the first hospital in Indiana, and one of the first in the nation, to utilize echocardiography to diagnose congenital heart defects
1971
- Indiana's first and only pediatric burn center opens at Riley
- Indiana's first neonatal intensive care unit opens at Riley
- The Parent Care Unit opens at Riley Hospital for Children with open visitation, participation and in-room sleeping accommodations for parents, creating a national model for family-centered care
1975
- The first staged Fontan procedure in Indiana is performed at Riley. The surgery keeps oxygenated blood and deoxygenated blood from mixing in the heart
1980
- Riley becomes the first hospital in Indiana to provide outpatient surgical care for children
1983
- Indiana's first pediatric cochlear implant procedure (to correct deafness) is performed at Riley
1986
- Indiana's first ECMO procedure (a form of heart-lung bypass for critically ill infants and children) is performed at Riley
1988
- Indiana's first pediatric liver transplant is performed at Riley
1989
- Indiana's first infant and newborn heart transplants are performed at Riley
1991
- The Herman B Wells Center for Pediatric Research opens at Riley Hospital for Children
1994
- Indiana's first and only pediatric cancer center, including the state's only stem cell transplant unit, opens at Riley
- Indiana's first pediatric cord blood transplant is performed at Riley
1997
- Riley Hospital for Children joins Indiana University Hospital and Methodist Hospital to form Clarian Health Partners
1997-2006
- Clarian Health Partners is listed among the nation's best hospitals by US News and World Report magazine for nine consecutive years
2000
- The Riley Outpatient Center opens as the nation's largest ambulatory care center for children
2001
- The Riley Sleep Disorders Center opens as the largest pediatric sleep lab in the world
2002
- Indiana's only dedicated unit for children with heart defects, the Riley Heart Center, opens
- Riley is one of just 19 hospitals in the country selected to perform Phase I pediatric cancer research protocols
- One of the nation's three largest autism centers, the Christian Sarkine Autism Treatment Center, opens at Riley
2003
- First intestinal and multi-organ transplants in Indiana performed at Riley
- First hospital in the Eastern United States and only one of two in the U.S. to receive special government permission to use and implant the Berlin Heart, a ventricular assist device. The Berlin Heart is a new way to treat complex cardiac problems
- First time Riley surgeons use Repiphysis, a prosthetic implanted in an arm or leg
- First hospital in Indiana to perform a pulmonary autograft mitral valve replacement, a revolutionary procedure to replace the mitral valve
2004
- Family as Faculty program, part of the Family-Centered Care Program, launched at Riley Hospital for Children
- Riley formalizes partnership with Deaconess Hospital in Evansville
- Riley celebrates 80th birthday
- Riley ranked as one of America's best children's hospitals according to Child Magazine
- Riley Launches Riley Connections - A Telemedicine Program, allowing Riley physicians to consult with out-of-town physicians and patients
2005
- Riley announces its $500 million, 10-year plan
- Riley Hospital for Children at Clarian North Medical Center opens
- Simon Family Tower patient tower work begins
- Riley NICU is recognized as among the best five in the nation, according to Child magazine
2006
- Child magazine ranked Riley Hospital 11th in the nation overall out of nearly 250 children's hospitals. The magazine also ranked the hospital's neonatal and pulmonary departments in the top 10.
- The Riley Children's Foundation received a $10 million gift from the Eli Lilly and Company Foundation that will be used to help establish a world-class pediatric diabetes treatment and care program at Riley Hospital for Children.
- Riley Hospital for Children at Clarian North opened the Center for Children's Cancer and Blood Diseases. The center provides hematology/
oncology services to patients and families.
- Riley is the first hospital in Indiana and among a few hospitals in the nation to use the Vertical Expandable Prosthetic Titanium Rib (VEPTR). The VEPTR is a curved, telescoping titanium device that's attached to the ribs and/or the spine to straighten and separate them so that the lungs develop properly.
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